REVISTA

Presente y futuro de los opioides en pequeños animales

Valoración Valoración: 4 Estrellas

Descripción: Revisión de los avances y en el conocimiento de los efectos de los opioides, su empleo de opioides, el desarrollo de nuevos fármacos y las perspectivas futuras.

TITULO FUENTE ORIGINAL:

The present and future of opioid analgesics in small animal practice

AUTORES:

Simon BT, Steagall PV

REVISTA ABREV.:

J Vet Pharmacol Ther

AÑO:

2016

DOI:

10.1111/jvp.12377

RESUMEN ORIGINAL:

Opioids are the cornerstone for the treatment of acute pain in small animal patients. This is primarily because of their remarkable safety profile, high efficacy, and benefit of reversibility. There have been some significant advances in our knowledge on opioid pharmacology and clinical usage in companion animal medicine. This review discusses the progression of opioid use in small animal... + Leer más

Opioids are the cornerstone for the treatment of acute pain in small animal patients. This is primarily because of their remarkable safety profile, high efficacy, and benefit of reversibility. There have been some significant advances in our knowledge on opioid pharmacology and clinical usage in companion animal medicine. This review discusses the progression of opioid use in small animal practice providing current misconceptions and controversies in light of routes of administration. Potential targets for research and drug development and novel therapies are discussed in addition to the concepts of glial cell modulators, individual variability, and opioid tolerance and hyperalgesia. The future brings an interesting perspective with the application of pharmacogenetics and individualized pain management in canine and feline practice.

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