REVISTA

Receptores opioides

Valoración Valoración: 4 Estrellas

Descripción: Receptores opioides: revisión sobre sus mecanismos de acción, ligandos endógenos y exógenos y tipos de receptores opioides.

TITULO FUENTE ORIGINAL:

Opiod receptors

AUTORES:

McDonald J, Lambert DG

REVISTA ABREV.:

Contin Educ Anaesth Crit Care Pain

AÑO:

2015

REFERENCIA:

15(5):219-224

DOI:

10.1093/bjaceaccp/mku041

RESUMEN ORIGINAL:

The opioid system comprises four types of receptor: μ- (MOP), δ- (DOP), κ-opioid and nociceptin (NOP). Opioid receptors all have selective endogenous peptides. Analgesia elicited by clinically applied opioids act predominantly via the MOP receptor. Tolerance to MOP receptor analgesics maybe attenuated by both NOP and DOP receptor antagonism.
Mixed-opioids...
+ Leer más

The opioid system comprises four types of receptor: μ- (MOP), δ- (DOP), κ-opioid and nociceptin (NOP). Opioid receptors all have selective endogenous peptides. Analgesia elicited by clinically applied opioids act predominantly via the MOP receptor. Tolerance to MOP receptor analgesics maybe attenuated by both NOP and DOP receptor antagonism.
Mixed-opioids represent a new focus in opioid receptor pharmacology.

- Leer menos