REVISTA

Actualización del uso de toxina botulínica para el tratamiento del dolor en personas

Descripción: Revisión sobre las nuevas indicaciones de la toxina botulínica y sus posibles complicacioines en medicina humana

TITULO FUENTE ORIGINAL:

Botulinum toxin update: new uses for pain and spasm

AUTORES:

Gevirtz C.

REVISTA ABREV.:

Topics in Pain Management

AÑO:

2013

REFERENCIA:

29(5):1-7.

DOI:

10.1097/01.TPM.0000438611.18223.9a

FECHA DE PUBLICACIÓN:

01/12/2013

RESUMEN ORIGINAL:

For a long time, botulinum toxin, produced by the bacterium Clostridium botulinum, had an image problem. It was known first and foremost as a stealthy poison that could survive the anaerobic environment of canned foods, so potent that it took only a miniscule amount to poison someone with botulism. It is the most acutely toxic substance known.Medical uses became evident by the 1960s, but so... + Leer más

For a long time, botulinum toxin, produced by the bacterium Clostridium botulinum, had an image problem. It was known first and foremost as a stealthy poison that could survive the anaerobic environment of canned foods, so potent that it took only a miniscule amount to poison someone with botulism. It is the most acutely toxic substance known.Medical uses became evident by the 1960s, but so did cosmetic ones, and before long, the image was associated with the so-called Botox parties, in which physicians injected botulinum toxin (BTX) in guests who sipped wine, nibbled on cheese, and waited their turn to pay in cash for injections to relax their glabellar lines.However, a growing body of evidence supports the analgesic and antispasmodic properties of this purified toxin. In an earlier article (Topics in Pain Management. 2003; vol. 19, no. 1), the basic pharmacology and use of BTX were presented. In the years since then, several dramatic new evidence-based indications have been adopted, and there is increasing promise that this deadly poison has turned into a major pain-fighting tool. This article addresses these new indications and the possible complications of botulinum therapy, and the potency of BTX.

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