REVISTA DESTACADA

Reducción de las necesidades de anestésico inhalatorio en el perro con una infusión de fentanilo-lidocaína-ketamina (FLK) en el perro

Descripción: La infusión de una combinación de fentanilo, lidocaína y ketamina producen un efecto analgésico que permite reducir considerablemente las dosis de isoflurano en el perro

TITULO FUENTE ORIGINAL:

Reduction of the minimum alveolar concentration of isoflurane in dogs using a constant rate of infusion of lidocaine-ketamine in combination with either morphine or fentanyl

AUTORES:

Aguado D, Benito J, Gómez de Segura IA

REVISTA ABREV.:

Vet J

AÑO:

2015

REFERENCIA:

189(1): 63-66

DOI:

10.1016/j.tvjl.2010.05.029.

RESUMEN ORIGINAL:

The objective of this study was to determine the effects of a constant rate of infusion of lidocaine and ketamine in combination with either morphine or fentanyl on the minimum alveolar concentration of isoflurane (MAC(ISO)) during ovariohysterectomy in dogs. Female dogs (n=44) were premedicated with acepromazine and midazolam. Anaesthesia was induced with propofol and maintained with... + Leer más

The objective of this study was to determine the effects of a constant rate of infusion of lidocaine and ketamine in combination with either morphine or fentanyl on the minimum alveolar concentration of isoflurane (MAC(ISO)) during ovariohysterectomy in dogs. Female dogs (n=44) were premedicated with acepromazine and midazolam. Anaesthesia was induced with propofol and maintained with isoflurane. Dogs received ketamine (0.6 mg/kg/h) and lidocaine (3 mg/kg/h) together with morphine (0.24 mg/kg/h; MLK) or fentanyl (0.0036 mg/kg/h; FLK). The control group received Ringer's lactate solution. A skin incision was used as the noxious stimulus. The MAC(ISO) value was obtained with Dixon's up-and-down method. MAC(ISO) was 0.7±0.0 vol.% in the control group, 0.3±0.0 vol.% in the MLK group (45% MAC reduction) and 0.0±0.0 vol.% in the FLK group (97% MAC reduction). A combination of fentanyl with lidocaine and ketamine decreased the MAC(ISO) in dogs; this decrease was more pronounced than that produced by morphine, lidocaine and ketamine.

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