REVISTA

Tramadol: farmacocinética y eficacia vía intravenosa y extradural en perros

Descripción: Tramadol vía Extradural proporciona buena analgesia intraoperatoria sin importantes efectos adversos, pero no es una vía de administración práctica en el postoperatorio

TITULO FUENTE ORIGINAL:

Pharmacokinetics and efficacy of intravenous and extradural tramadol in dogs

AUTORES:

Vettorato E, Zonca A, Isola M, Villa R, Gallo M, Ravasio G, Beccaglia M, Montesissa C, Cagnardi P.

REVISTA ABREV.:

Vet J

AÑO:

2010

REFERENCIA:

Mar;183(3):310-315

DOI:

10.1016/j.tvjl.2008.11.002

FECHA DE PUBLICACIÓN:

03/03/2010

RESUMEN ORIGINAL:

Tramadol is a synthetic opioid agonist used extensively in human and, to a lesser extent, veterinary medicine throughout the world. The clinical efficacy and pharmacokinetic profile of intravenous (IV) and extradural (ED) tramadol (2 mg/kg) and its o-desmethyl metabolite were studied in dogs undergoing tibial plateau levelling osteotomy (TPLO). Intra-operative cardiorespiratory variables were... + Leer más

Tramadol is a synthetic opioid agonist used extensively in human and, to a lesser extent, veterinary medicine throughout the world. The clinical efficacy and pharmacokinetic profile of intravenous (IV) and extradural (ED) tramadol (2 mg/kg) and its o-desmethyl metabolite were studied in dogs undergoing tibial plateau levelling osteotomy (TPLO). Intra-operative cardiorespiratory variables were monitored and post-operative pain was assessed using the short form of the Glasgow Composite Pain Scale. A rapid (

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