REVISTA

Antagonistas NMDA y dolor: ketamina

Valoración Valoración: 5 Estrellas

Descripción: La ketamina es un fármaco de uso común en caballos como anestésico y más recientemente como analgésico

TITULO FUENTE ORIGINAL:

NMDA receptor antagonists and pain: ketamine

AUTORES:

Muir WW

REVISTA ABREV.:

Vet Clin North Am Equine Pract

AÑO:

2010

REFERENCIA:

26(3):565-78

DOI:

10.1016/j.cveq.2010.07.009.

RESUMEN ORIGINAL:

N-Methyl-D-aspartate (NMDA) is a synthetic chemical binding molecule (ligand) that selectively binds to the "slow response" glutamate NMDA receptor (NMDAR). NMDARs are important for normal brain function and play a central role in learning, memory, and the development of central nervous system hyperactive states. Diverse chemicals belonging to various drug families have demonstrated NMDAR... + Leer más

N-Methyl-D-aspartate (NMDA) is a synthetic chemical binding molecule (ligand) that selectively binds to the "slow response" glutamate NMDA receptor (NMDAR). NMDARs are important for normal brain function and play a central role in learning, memory, and the development of central nervous system hyperactive states. Diverse chemicals belonging to various drug families have demonstrated NMDAR antagonistic effects. Ketamine has been shown to produce antihyperalgesic effects produced by incision and tissue or nerve damage, and has become popular in equine practice as an anesthetic and more recently as an analgesic for standing surgical procedures and the treatment of laminitis. This review focuses on the development of ketamine as an anesthetic and analgesic in horses.

- Leer menos

COMENTARIO DE IGNACIO, ?LVAREZ G?MEZ DE SEGURA

Actualización del empleo de la ketamina en el caballo centrado no solo en el uso como anestésico sino en los nuevos usos como analgésico como puede ser durante la cirugía en el caballo en la estación u otros procesos que cursan con dolor como la infosura.

ENLACES DE INTERÉS

Página inicial: : http://www.sciencedirect.com/science/article/[...]